The Anti-SARS-CoV-2 ORF3a Antibody (CAB20234) is a vital tool for research on the ORF3a protein of the SARS-CoV-2 virus, which plays a role in viral replication and pathogenesis. This polyclonal antibody, produced in rabbits, exhibits high reactivity with SARS-CoV-2 samples and is validated for use in various applications, including Western blotting.With the ability to specifically bind to the ORF3a protein, this antibody enables accurate detection and analysis of the viral protein in infected cells, aiding in the study of SARS-CoV-2 pathogenesis and potential therapeutic interventions.
Its use is essential for advancing our understanding of the virus and developing effective strategies to combat COVID-19.Researchers in virology, immunology, and infectious diseases will find this antibody invaluable for investigating the mechanisms of SARS-CoV-2 infection and identifying potential targets for antiviral treatments. Stay ahead in the fight against COVID-19 with the Anti-SARS-CoV-2 ORF3a Antibody (CAB20234).
Product Name:
SARS-CoV-2 ORF3A Rabbit Polyclonal Antibody
SKU:
CAB20234
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
SARS-CoV-2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of coronavirus ORF3A (YP_009724391.1).
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ ORF3a encodes a viral accessory protein. Based on its similarity to other coronavirus proteins, ORF3a protein is thought to be a protein with ion channel activity (viroporin) that activates the NLRP3 inflammasome. ORF3a may also play a role in virus replication and pathogenesis.
Purification Method:
Affinity purification
Gene ID:
43740569
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using SARS-CoV-2 ORF3A Rabbit pAb (CAB20234) at 1:5000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
