null

SARS-CoV-2 NSP7 Rabbit Polyclonal Antibody (CAB20201)

SKU:
CAB20201
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Virus
Host Species:
Rabbit
Isotype:
IgG
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

SARS-CoV-2 NSP7 Rabbit Polyclonal Antibody (CAB20201)

The Anti-SARS-CoV-2 NSP7 Antibody (CAB20201) is a crucial tool for research involving the NSP7 protein of the SARS-CoV-2 virus, which plays a key role in viral replication. This polyclonal antibody, produced in rabbits, is highly specific to SARS-CoV-2 NSP7 and has been validated for use in various applications, such as Western blotting and immunofluorescence.With the ongoing global pandemic caused by the SARS-CoV-2 virus, understanding the function and behavior of NSP7 is essential for developing effective treatments and vaccines.

This antibody enables researchers to detect and analyze the NSP7 protein in infected cells, providing valuable insights into viral replication mechanisms and potential targets for antiviral therapies.Overall, the Anti-SARS-CoV-2 NSP7 Antibody (CAB20201) is a valuable tool for studies focused on the SARS-CoV-2 virus, offering researchers the ability to investigate the molecular interactions and pathways involved in viral replication, ultimately contributing to the development of strategies to combat COVID-19.

Product Name:SARS-CoV-2 NSP7 Rabbit Polyclonal Antibody
SKU:CAB20201
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-83 of coronavirus NSP7 (YP_009742614.1).
Sequence:SKMS DVKC TSVV LLSV LQQL RVES SSKL WAQC VQLH NDIL LAKD TTEA FEKM VSLL SVLL SMQG AVDI NKLC EEML DNRA TLQ
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Positive Sample:293T
Calculated MW:141kDa
Observed MW:10kDa

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ ORF1ab, the largest gene, contains overlapping open reading frames that encode polyproteins PP1ab and PP1a. The polyproteins are cleaved to yield 16 nonstructural proteins, NSP1-16. Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based on similarity to other coronaviruses, include the papain-like proteinase protein (NSP3), 3C-like proteinase (NSP5), RNA-dependent RNA polymerase (NSP12, RdRp), helicase (NSP13, HEL), endoRNAse (NSP15), 2'-O-Ribose-Methyltransferase (NSP16) and other nonstructural proteins. SARS-CoV-2 nonstructural proteins are responsible for viral transcription, replication, proteolytic processing, suppression of host immune responses and suppression of host gene expression. The RNA-dependent RNA polymerase is a target of antiviral therapies.

Purification Method:Affinity purification
Gene ID:43740578
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of normal 293T cells 293T transfected with NSP7 Protein, using SARS-CoV-2 NSP7 Rabbit pAb (CAB20201) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

Related Products