The Anti-S1PR5 Antibody (CAB20164) is an essential tool for research involving the sphingosine-1-phosphate receptor 5 (S1PR5), a key player in various cellular processes. This specific antibody, developed using advanced technologies, is highly reactive with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.S1PR5 is a G protein-coupled receptor that plays a crucial role in cell proliferation, migration, and survival, making it a potential target for therapeutic interventions in cancer and other diseases.
By binding to the S1PR5 protein, this antibody enables precise detection and analysis of S1PR5 expression in different cell types, facilitating research in immunology, oncology, and other fields.Researchers studying the role of S1PR5 in disease pathogenesis, drug development, and cellular signaling pathways will find this antibody invaluable in their experiments. With its high specificity and sensitivity, the Anti-S1PR5 Antibody (CAB20164) offers reliable results and is a valuable tool for advancing scientific understanding in various biomedical research areas.
Product Name:
S1PR5 Rabbit Polyclonal Antibody
SKU:
CAB20164
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 307-398 of human S1PR5 (NP_110387.1).
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.
Purification Method:
Affinity purification
Gene ID:
53637
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using S1PR5 Rabbit pAb (CAB20164) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
