null

S1PR5 Rabbit Polyclonal Antibody (CAB20164)

SKU:
CAB20164
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
EDG8
S1P5
Edg-8
SPPR-1
SPPR-2
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:S1PR5 Rabbit Polyclonal Antibody
SKU:CAB20164
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 307-398 of human S1PR5 (NP_110387.1).
Sequence:TLTN RDLR HALL RLVC CGRH SCGR DPSG SQQS ASAA EASG GLRR CLPP GLDG SFSG SERS SPQR DGLD TSGS TGSP GAPT AART LVSE PAAD
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:EDG8; S1P5; Edg-8; SPPR-1; SPPR-2; S1PR5
Positive Sample:MCF7,Jurkat
Conjugate:Unconjugated
Cellular Localization:cytoplasm, plasma membrane
Calculated MW:42kDa
Observed MW:50kDa

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.

Purification Method:Affinity purification
Gene ID:53637
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using S1PR5 Rabbit pAb (CAB20164) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

Related Products