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S100A6 Rabbit Monoclonal Antibody (CAB3461)

SKU:
CAB3461
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
2A9
5B10
CABP
CACY
PRA
Research Area:
Epigenetics and Nuclear Signaling
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:S100A6 Rabbit Monoclonal Antibody
SKU:CAB3461
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human S100A6 (P06703).
Sequence:MACP LDQA IGLL VAIF HKYS GREG DKHT LSKK ELKE LIQK ELTI GSKL QDAE IARL MEDL DRNK DQEV NFQE YVTF LGAL ALIY NEAL KG
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:100 - 1:500
Synonyms:2A9; PRA; 5B10; CABP; CACY; S10A6; S100A6
Positive Sample:HeLa,C2C12,HUVEC,Mouse lung,Mouse spleen,Rat spleen
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Cytoplasm, Cytoplasmic side, Nucleus envelope, Peripheral membrane protein.
Calculated MW:10kDa
Observed MW:10kDa

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

Purification Method:Affinity purification
Gene ID:6277
Clone Number:ARC2005
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using S100A6 Rabbit mAb (CAB3461) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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