The Anti-S100A4 Antibody (CAB19109) is a valuable tool for researchers studying the S100A4 protein, which plays a significant role in cancer progression and metastasis. This polyclonal antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in various applications such as Western blot and immunohistochemistry.S100A4, a member of the S100 protein family, is involved in cell motility, invasion, and angiogenesis, making it a key player in tumor growth and metastasis.
By targeting S100A4 with this antibody, researchers can detect and analyze its expression in different cell types, providing insights into its role in cancer biology.Understanding the function of S100A4 is crucial for developing targeted therapies for cancer patients. By using this antibody, researchers can further explore the mechanisms by which S100A4 promotes tumor progression, paving the way for new treatment strategies in oncology.
Product Name:
FSP1/S100A4 Rabbit Monoclonal Antibody
SKU:
CAB19109
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2-101 of human S100A4 (P26447).
extracellular exosome, extracellular region, extracellular space, neuron projection, nucleus, perinuclear region of cytoplasm
Calculated MW:
12kDa
Observed MW:
12kDa
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method:
Affinity purification
Gene ID:
6275
Clone Number:
ARC0475
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using FSP1/S100A4 Rabbit mAb (CAB19109) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
