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Anti-RRAS Antibody (CAB20243)

SKU:
CAB20243
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
RRAS
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Description

Product Name:RRAS Rabbit pAb
Product Code:CAB20243
Size:50uL, 100uL
Synonyms:RRAS
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant protein of human RRAS
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Immunogen:Recombinant protein of human RRAS
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:6237
Uniprot:P10301
Cellular Location:Cell membrane, Cytoplasmic side, Lipid-anchor
Calculated MW:23kDa
Observed MW:Refer to figures
UniProt Protein Function:RRas: a small G protein of the Ras family. Promotes focal adhesion formation by signaling to FAK and p130(Cas). Promotes tumor growth of cervical epithelial cells and increases their migration potential over collagen through a pathway that involves PI 3-K.
UniProt Protein Details:

Protein type:G protein, monomeric, Ras; Motility/polarity/chemotaxis; G protein, monomeric; G protein

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: focal adhesion; plasma membrane

Molecular Function:GDP binding; GTPase activity; protein binding; protein complex binding

Biological Process: leukocyte differentiation; positive regulation of angiogenesis; Ras protein signal transduction; regulation of protein kinase B signaling cascade

NCBI Summary:The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015]
UniProt Code:P10301
NCBI GenInfo Identifier:133486
NCBI Gene ID:6237
NCBI Accession:P10301.1
UniProt Secondary Accession:P10301,Q6FH12,
UniProt Related Accession:P10301
Molecular Weight:23,480 Da
NCBI Full Name:Ras-related protein R-Ras
NCBI Synonym Full Names:related RAS viral (r-ras) oncogene homolog
NCBI Official Symbol:RRAS  
NCBI Protein Information:ras-related protein R-Ras
UniProt Protein Name:Ras-related protein R-Ras
UniProt Synonym Protein Names:p23
Protein Family:Ras-related protein
UniProt Gene Name:RRAS  
UniProt Entry Name:RRAS_HUMAN

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