The RPS6KA1/2/3 Polyclonal Antibody (CAB20285) is a valuable tool for researchers studying the RPS6KA family of proteins involved in cellular signaling pathways. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the RPS6KA1, RPS6KA2, and RPS6KA3 proteins, this antibody enables the detection and analysis of these important molecules in various cell types.The RPS6KA family of proteins plays a crucial role in cell growth, proliferation, and survival, making them key targets for cancer research and drug development.
Understanding the functions and interactions of RPS6KA1, RPS6KA2, and RPS6KA3 is essential for uncovering their roles in diseases such as cancer and neurological disorders. This antibody provides researchers with a powerful tool to investigate the complex signaling pathways involving the RPS6KA proteins, ultimately leading to a better understanding of their implications in human health and disease.
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
6195/ 6196/ 6197
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RPS6KA1/RPS6KA2/RPS6KA3 Rabbit pAb (CAB20285) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
