The Anti-RPB3 (POLR2C) Antibody (CAB9744) is a highly specific tool for researchers studying the RPB3 (POLR2C) protein, a subunit of RNA polymerase II involved in transcription. This antibody, produced in rabbits, is optimized for use in Western blot applications and shows strong reactivity with human samples.The RPB3 (POLR2C) protein is essential for transcription initiation and regulation, making it a key target for studies in molecular biology and gene expression. By specifically binding to RPB3 (POLR2C), this antibody allows for accurate detection and analysis of the protein in various cell types, providing valuable insights into transcription mechanisms and gene regulation.
Researchers investigating processes such as RNA synthesis, transcriptional control, and gene expression will benefit from the use of the Anti-RPB3 (POLR2C) Antibody (CAB9744) in their experiments. Its high specificity and sensitivity make it an essential tool for advancing our understanding of transcriptional processes and their impact on cellular function.
Product Name:
POLR2C Rabbit Monoclonal Antibody
SKU:
CAB9744
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RPB3/POLR2C (P19387).
This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21.
Purification Method:
Affinity purification
Gene ID:
5432
Clone Number:
ARC1729
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using RPB3/POLR2C Rabbit mAb (CAB9744) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
