The Anti-RHOG Antibody (CAB19302) is a valuable tool for researchers studying RHOG, a small GTPase protein involved in regulating various cellular processes such as cell migration and cytoskeletal organization. This polyclonal antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications.RHOG plays a crucial role in signal transduction pathways that control actin dynamics, making it a key player in processes like cell adhesion and migration.
Dysregulation of RHOG signaling has been linked to diseases such as cancer, making it an important target for research into potential therapeutic interventions.By using the Anti-RHOG Antibody, researchers can detect and analyze the expression levels of RHOG in different cell types, providing insights into its function and potential implications in disease pathology. This antibody is a valuable tool for studies in cell biology, cancer research, and drug development aimed at targeting RHOG-related pathways.
Product Name:
RHOG Rabbit Polyclonal Antibody
SKU:
CAB19302
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human RHOG (NP_001656.2).
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X.
Purification Method:
Affinity purification
Gene ID:
391
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RHOG Rabbit pAb (CAB19302) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
