The RGAP1 Polyclonal Antibody (CAB19236) is a powerful tool for researchers studying the RGAP1 protein, which is involved in regulating immune responses and inflammation. This high-quality antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications.RGAP1, also known as Regulator of G-protein Signaling 1, plays a key role in modulating signaling pathways involved in immune cell function and inflammatory responses. By targeting RGAP1 with this antibody, researchers can detect and analyze the protein in various cell types, making it ideal for studies in immunology and inflammation-related research.
The role of RGAP1 in immune regulation and inflammatory processes makes it a promising target for investigating diseases such as autoimmune disorders, cancer, and chronic inflammatory conditions. By understanding the function and activity of RGAP1, researchers can gain valuable insights that may lead to the development of novel therapeutic strategies for these challenging conditions.
Product Name:
RGAP1 Rabbit Monoclonal Antibody
SKU:
CAB19236
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RGAP1 (Q9H0H5).
This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.
Purification Method:
Affinity purification
Gene ID:
29127
Clone Number:
ARC2394
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from PC-12 cells, using RGAP1 Rabbit mAb (CAB19236) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
