The RBP4 Polyclonal Antibody (CAB8807) is a valuable tool for research involving RBP4, a protein known for its role in retinol transport and metabolism. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.RBP4, also known as retinol-binding protein 4, is a carrier protein that plays a crucial role in the transport of vitamin A in the blood. Its involvement in metabolic processes and its association with conditions like obesity and insulin resistance make it an important target for research in the fields of metabolism, endocrinology, and obesity-related disorders.
By using the RBP4 Polyclonal Antibody (CAB8807), researchers can detect and analyze RBP4 protein levels in different cell types, providing valuable insights into its function and potential implications in disease states. This antibody is an essential tool for studies aiming to unravel the complexities of retinol metabolism and its impact on health and disease.
Product Name:
RBP4 Rabbit Monoclonal Antibody
SKU:
CAB8807
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 102-201 of human RBP4 (P02753).
Extracellular exosome, Extracellular region, Extracellular space
Calculated MW:
21kDa
Observed MW:
22kDa
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
Purification Method:
Affinity purification
Gene ID:
5950
Clone Number:
ARC1311
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of HepG2 cells, using RBP4 antibody (CAB8807) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
