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RBFOX2 Polyclonal Antibody (CAB20810)

SKU:
CAB20810
Product Type:
Antibody
Antibody Type:
Secondary Antibody
Host Species:
Mouse
Isotype:
IgG
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:RBFOX2 Polyclonal Antibody
SKU:CAB20810
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human RBFOX2 (NP_001026865.1).
Sequence:MEKK KMVT QGNQ EPTT TPDA MVQP FTTI PFPP PPQN GIPT EYGV PHTQ DYAG QTGE HNLT LYGS TQAH GEQS SNSP STQN GSLT TEGG AQTD GQQS QTQS SENS ESKS TP
Tested Applications:WB ELISA
Recommended Dilution:WB,1:1000 - 1:5000
Synonyms:RTA; fxh; FOX2; RBM9; Fox-2; HNRBP2; HRNBP2; dJ106I20.3; RBFOX2
Positive Sample:U-87MG,LO2,HeLa
Conjugate:Unconjugated
Cellular Localization:cytoplasm, nucleoplasm, nucleus
Calculated MW:41kDa
Observed MW:50kDa/60kDa

This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:23543
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using RBFOX2 Rabbit pAb (CAB20810) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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