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RAIDD/CRADD Rabbit Monoclonal Antibody (CAB8664)

SKU:
CAB8664
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
MRT34
RAIDD
Research Area:
Cell Death
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:RAIDD/CRADD Rabbit Monoclonal Antibody
SKU:CAB8664
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 70-150 of human CRADD (P78560).
Sequence:DTFL DSLQ EFPW VREK LKKA REEA MTDL PAGD RLTG IPSH ILNS SPSD RQIN QLAQ RLGP EWEP MVLS LGLS QTDI YRCK A
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200
Synonyms:MRT34; RAIDD; RAIDD/CRADD
Positive Sample:293T,K-562,Rat liver,Rat heart
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:23kDa
Observed MW:23kDa

This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:8738
Clone Number:ARC1771
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using RAIDD/CRADD Rabbit mAb (CAB8664) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.

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