RAIDD/CRADD Rabbit Monoclonal Antibody (CAB8664)
- SKU:
- CAB8664
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MRT34
- RAIDD
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | RAIDD/CRADD Rabbit Monoclonal Antibody |
SKU: | CAB8664 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 70-150 of human CRADD (P78560). |
Sequence: | DTFL DSLQ EFPW VREK LKKA REEA MTDL PAGD RLTG IPSH ILNS SPSD RQIN QLAQ RLGP EWEP MVLS LGLS QTDI YRCK A |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | MRT34; RAIDD; RAIDD/CRADD |
Positive Sample: | 293T,K-562,Rat liver,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 23kDa |
Observed MW: | 23kDa |
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 8738 |
Clone Number: | ARC1771 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |