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RAIDD/CRADD Rabbit Monoclonal Antibody (CAB8663)

SKU:
CAB8663
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
MRT34
RAIDD
Research Area:
Cell Death
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:RAIDD/CRADD Rabbit Monoclonal Antibody
SKU:CAB8663
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100-199 of human RAIDD/CRADD (NP_003796.1).
Sequence:GDRL TGIP SHIL NSSP SDRQ INQL AQRL GPEW EPMV LSLG LSQT DIYR CKAN HPHN VQSQ VVEA FIRW RQRF GKQA TFQS LHNG LRAV EVDP SLLL HMLE
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:MRT34; RAIDD; RAIDD/CRADD
Positive Sample:HT-29,293T,K-562
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus
Calculated MW:23kDa
Observed MW:23kDa

This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:8738
Clone Number:ARC1770
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using RAIDD/CRADD Rabbit mAb (CAB8663) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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