The Anti-RAD54L Antibody (CAB20181) is a valuable tool for researchers studying RAD54L, a key protein involved in DNA repair and recombination processes. This polyclonal antibody, produced in-house using rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications.RAD54L is a crucial factor in maintaining genomic stability and promoting efficient DNA repair mechanisms, making it essential for cell survival and preventing the development of genetic mutations. By targeting the RAD54L protein, researchers can investigate its role in DNA damage response pathways and explore its potential as a therapeutic target for cancer treatment.
With its ability to specifically detect RAD54L in various cell types, this antibody is well-suited for studies in molecular biology, genetics, and oncology. By elucidating the function of RAD54L and its interactions with other DNA repair proteins, researchers can gain valuable insights into the mechanisms underlying genomic maintenance and the development of targeted therapies for cancer and other genetic disorders.
Product Name:
RAD54L Rabbit Polyclonal Antibody
SKU:
CAB20181
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 648-747 of human RAD54L (Q92698).
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.
Purification Method:
Affinity purification
Gene ID:
8438
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAD54L Rabbit pAb (CAB20181) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
