Rad21 Rabbit Monoclonal Antibody (CAB19749)
- SKU:
- CAB19749
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CDLS4
- HR21
- HRAD21
- MCD1
- NXP1
- SCC1
- hHR21
Frequently bought together:
Description
Product Name: | Rad21 Rabbit Monoclonal Antibody |
SKU: | CAB19749 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 532-631 of human Rad21 (O60216). |
Sequence: | EKED DEEE EDED ASGG DQDQ EERR WNKR TQQM LHGL QRAL AKTG AESI SLLE LCRN TNRK QAAA KFYS FLVL KKQQ AIEL TQEE PYSD IIAT PGPR FHII |
Tested Applications: | WB ChIP ChIP-seq ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 ChIP,5μg antibody for 10μg-15μg of ChromatinChIP-seq,1:50 - 1:100 |
Synonyms: | MGS; HR21; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21; Rad21 |
Positive Sample: | HeLa,A549,NIH/3T3,C6 |
Conjugate: | Unconjugated |
Cellular Localization: | Condensed nuclear chromosome, Cytosol, nuclear matrix, Nucleoplasm, Nucleus, Spindle pole |
Calculated MW: | 72kDa |
Observed MW: | 130kDa |
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
Purification Method: | Affinity purification |
Gene ID: | 5885 |
Clone Number: | ARC2276 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |