Rad21 Rabbit Polyclonal Antibody (CAB18850)
- SKU:
- CAB18850
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CDLS4
- HR21
- HRAD21
- MCD1
- NXP1
- SCC1
- hHR21
Frequently bought together:
Description
Product Name: | Rad21 Rabbit Polyclonal Antibody |
SKU: | CAB18850 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 281-420 of human Rad21 (NP_006256.1). |
Sequence: | VDPV EPMP TMTD QTTL VPNE EEAF ALEP IDIT VKET KAKR KRKL IVDS VKEL DSKT IRAQ LSDY SDIV TTLD LAPP TKKL MMWK ETGG VEKL FSLP AQPL WNNR LLKL FTRC LTPL VPED LRKR RKGG EADN LDEF LKEF |
Tested Applications: | WB IHC-P IF/ICC IP ChIP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsChIP,5μg antibody for 10μg-15μg of Chromatin |
Synonyms: | MGS; HR21; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21; Rad21 |
Positive Sample: | Jurkat,Mouse thymus,C6 |
Cellular Localization: | condensed nuclear chromosome, cytosol, nuclear matrix, nucleoplasm, nucleus, spindle pole |
Calculated MW: | 72kDa |
Observed MW: | 130kDa |
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
Purification Method: | Affinity purification |
Gene ID: | 5885 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |