The Anti-Rab5 Antibody (CAB12304) is a high-quality antibody designed for research involving Rab5, a key regulator of early endosome fusion and trafficking within cells. This antibody, raised in rabbits, is highly specific and validated for use in various applications such as immunofluorescence and immunoprecipitation.Rab5 is a small GTPase protein that plays a crucial role in controlling the transport of proteins and lipids in the endocytic pathway. Dysregulation of Rab5 has been linked to various diseases, including cancer and neurodegenerative disorders.
By targeting Rab5 with this antibody, researchers can investigate its role in these pathological conditions and potentially identify new therapeutic targets.This Anti-Rab5 Antibody is an essential tool for studying cellular processes involving endosomal trafficking and could provide valuable insights into the molecular mechanisms underlying disease development. With its high specificity and sensitivity, this antibody offers reliable results for researchers in the fields of cell biology, oncology, and neuroscience.
Product Name:
RAB5A Rabbit Monoclonal Antibody
SKU:
CAB12304
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 116-215 of human RAB5AA (P20339).
Enables GDP binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including amyloid-beta clearance by transcytosis; early endosome to late endosome transport; and regulation of exocytosis. Located in several cellular components, including cytoplasmic side of early endosome membrane; nucleoplasm; and terminal bouton.
Purification Method:
Affinity purification
Gene ID:
5868
Clone Number:
ARC0297
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RAB5AA Rabbit mAb (CAB12304) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
