The Anti-QSOX1 Antibody (CAB4060) is a valuable tool for researchers studying QSOX1, a key enzyme involved in the regulation of protein folding and maturation in the endoplasmic reticulum. This polyclonal antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting QSOX1 in human samples, making it suitable for use in various research applications such as Western blotting.QSOX1, or quiescin-sulfhydryl oxidase 1, plays a crucial role in the oxidative protein folding pathway, which is essential for the correct folding and stability of secretory proteins. Dysregulation of QSOX1 has been associated with various diseases, including cancer and neurodegenerative disorders.
Research into the function and regulation of QSOX1 is vital for understanding its implications in disease pathology and exploring potential therapeutic interventions.With its ability to specifically recognize QSOX1 in a variety of cell types, the Anti-QSOX1 Antibody (CAB4060) is a valuable tool for investigating the role of QSOX1 in health and disease. Its high reactivity and reliability make it an indispensable asset for studies in molecular biology, biochemistry, and biomedical research.
Product Name:
QSOX1 Rabbit Polyclonal Antibody
SKU:
CAB4060
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human QSOX1 (NP_001004128.1).
This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5768
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using QSOX1 antibody (CAB4060) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
