The Anti-PTPRR Antibody (CAB20981) is a vital tool for researchers studying PTPRR, a protein tyrosine phosphatase receptor implicated in various cellular processes. This polyclonal antibody, generated in rabbits, has high specificity and sensitivity for human samples, making it suitable for a range of applications including Western blotting. By targeting the PTPRR protein, researchers can detect and analyze its expression in different cell types, facilitating investigations into the role of PTPRR in biological pathways such as cell signaling and development.PTPRR, also known as protein tyrosine phosphatase receptor type R, is involved in regulating phosphorylation events and modulating cellular responses to external stimuli.
Its function in signaling cascades and cellular communication highlights its potential as a therapeutic target for diseases such as cancer, neurological disorders, and metabolic conditions. By elucidating the mechanisms by which PTPRR influences cellular behavior, researchers can uncover new insights into disease pathogenesis and identify novel treatment strategies aimed at restoring normal cellular function.
Product Name:
PTPRR Monoclonal Antibody
SKU:
CAB20981
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTPRR (Q15256).
Cell membrane, Cytoplasm, Single-pass type I membrane protein, perinuclear region, perinuclear region.
Calculated MW:
74kDa
Observed MW:
74kDa
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12.
Purification Method:
Affinity purification
Gene ID:
5801
Clone Number:
ARC2973
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PTPRR antibody (CAB20981) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
