The Anti-PTBP2 Antibody (CAB9124) is a vital tool for researchers studying PTBP2, a key protein involved in post-transcriptional regulation of gene expression. This antibody, produced in rabbits, exhibits high specificity and sensitivity when used in applications such as Western blotting and immunohistochemistry. By binding to PTBP2, this antibody enables precise detection and analysis of the protein in various cells and tissues, making it indispensable for investigations in molecular biology and developmental biology.PTBP2, also known as polypyrimidine tract-binding protein 2, plays a crucial role in RNA processing and alternative splicing, thereby influencing the diversity of mRNA transcripts and protein isoforms generated in cells.
Dysregulation of PTBP2 has been linked to various diseases, including cancer and neurodevelopmental disorders, highlighting its importance as a potential therapeutic target. By elucidating the function of PTBP2, researchers can uncover valuable insights into the molecular mechanisms underlying disease pathology and potentially identify novel treatment strategies.
Product Name:
PTBP2 Rabbit Monoclonal Antibody
SKU:
CAB9124
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTBP2 (Q9UKA9).
The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily in the brain. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
58155
Clone Number:
ARC1798
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PTBP2 Rabbit mAb (CAB9124) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
