The Anti-PRRX2 Antibody (CAB20558) is a valuable tool for research involving the PRRX2 protein, which plays a crucial role in various cellular processes related to development and differentiation. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in a range of applications including Western blotting and immunofluorescence.PRRX2, a transcription factor involved in embryonic development and tissue remodeling, has been implicated in various diseases such as cancer and fibrosis.
By targeting PRRX2 with this antibody, researchers can gain insights into its function and potential therapeutic applications in these and other pathological conditions.With its high specificity and sensitivity, the Anti-PRRX2 Antibody (CAB20558) is a valuable tool for studying the role of PRRX2 in cellular processes and disease pathology, offering researchers new avenues for exploration and discovery in the fields of biology and medicine.
Product Name:
PRRX2 Rabbit Polyclonal Antibody
SKU:
CAB20558
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-253 of human PRRX2 (NP_057391.1).
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.
Purification Method:
Affinity purification
Gene ID:
51450
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PRRX2 antibody (CAB20558) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
