The PRP19 Polyclonal Antibody (CAB9660) is a valuable tool for researchers studying the PRP19 protein, which plays a key role in pre-mRNA splicing and DNA repair processes. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it suitable for Western blot and immunofluorescence applications.PRP19, also known as pre-mRNA processing factor 19, is essential for maintaining genome stability and proper gene expression. Dysregulation of PRP19 has been implicated in a variety of diseases, including cancer and neurodegenerative disorders.
By using the PRP19 Polyclonal Antibody, researchers can accurately detect and analyze PRP19 expression levels in different cell types, advancing our understanding of its function in various biological processes.This antibody is a reliable tool for investigating the role of PRP19 in cellular pathways and disease development, offering valuable insights into potential therapeutic targets and treatment strategies. Its high specificity and sensitivity make it an essential component in studies related to molecular biology, genetics, and cancer research.
Product Name:
PRP19 Rabbit Monoclonal Antibody
SKU:
CAB9660
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 400-504 of human PRPF19(Q9UMS4).
Enables identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including DNA damage checkpoint signaling; cellular protein metabolic process; and mRNA splicing, via spliceosome. Acts upstream of or within protein polyubiquitination. Located in cytoplasm; nuclear speck; and site of double-strand break. Part of Prp19 complex and U2-type catalytic step 2 spliceosome. Colocalizes with DNA replication factor A complex.
Purification Method:
Affinity purification
Gene ID:
27339
Clone Number:
ARC1685
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PRP19 Rabbit mAb (CAB9660) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
