The Anti-Prolactin Receptor Antibody (CAB4121) is a high-quality antibody designed for research involving the prolactin receptor, a key player in regulating various physiological processes, including lactation, reproduction, and immune modulation. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. The anti-prolactin receptor antibody specifically binds to the prolactin receptor protein, allowing for accurate detection and analysis in a variety of cell types. Its utility in studying immune modulation, hormonal regulation, and the implications of prolactin signaling in diseases like breast cancer and infertility makes it an invaluable tool for researchers in the fields of endocrinology, oncology, and reproductive biology.
Understanding the role of the prolactin receptor in immune function and its implications in various health conditions is essential for developing targeted therapies and interventions. With its high specificity and sensitivity, the anti-prolactin receptor antibody (CAB4121) offers researchers a reliable tool for advancing our understanding of prolactin receptor biology and its potential therapeutic applications.
Product Name:
Prolactin Receptor Rabbit Monoclonal Antibody
SKU:
CAB4121
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Prolactin Receptor (P16471).
Cell surface, Endosome lumen, External side of plasma membrane, Extracellular region, Plasma membrane
Calculated MW:
70kDa
Observed MW:
95kDa
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
Purification Method:
Affinity purification
Gene ID:
5618
Clone Number:
ARC2123
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Prolactin Receptor Rabbit mAb (CAB4121) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
