The PROK1 Polyclonal Antibody (CAB19268) is a valuable tool for researchers studying PROK1, a protein known for its role in angiogenesis and immune regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the PROK1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it suitable for investigations in fields such as immunology and oncology.
PROK1, also referred to as prokineticin 1, is a multifunctional protein involved in various physiological processes, including vascular development and inflammation. Its ability to induce angiogenesis and modulate immune responses makes it a promising target for research on diseases like cancer and autoimmune disorders. By elucidating the mechanisms of PROK1 activity, researchers can gain insights that could lead to the development of novel therapeutic strategies for treating these conditions.
Product Name:
PROK1 Rabbit Monoclonal Antibody
SKU:
CAB19268
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human PROK1 (P58294).
The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.
Purification Method:
Affinity purification
Gene ID:
84432
Clone Number:
ARC2439
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PROK1 antibody (CAB19268) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
