The Anti-PRMT7 Antibody (CAB20975) is a valuable tool for researchers studying PRMT7, an enzyme involved in various cellular processes such as gene expression regulation and protein signaling. This polyclonal antibody, produced in rabbits, exhibits high specificity and sensitivity towards PRMT7 in human samples, making it an excellent choice for Western blot applications.PRMT7, a member of the protein arginine methyltransferase family, is known to participate in the methylation of various proteins, thereby affecting their functions and interactions within the cell. Its role in epigenetic regulation and post-translational modifications makes it a key player in cell biology research, particularly in fields like cancer biology and developmental biology.
By targeting PRMT7 with this antibody, researchers can gain valuable insights into its expression levels, subcellular localization, and potential interactions with other proteins. This information is crucial for understanding the mechanisms underlying PRMT7-mediated processes and for identifying potential therapeutic targets for diseases associated with dysregulated protein methylation.
Product Name:
PRMT7 Monoclonal Antibody
SKU:
CAB20975
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PRMT7 (Q9NVM4).
This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients.
Purification Method:
Affinity purification
Gene ID:
54496
Clone Number:
ARC2967
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PRMT7 antibody (CAB20975) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
