The Anti-PRLR Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0288) is specifically designed for research involving the PRLR protein, a key receptor involved in hormone signaling pathways. This antibody, developed using cutting-edge technology, is highly specific and sensitive for detecting PRLR in various tissues and cell types.The PRLR protein plays a crucial role in regulating cell growth, differentiation, and lactation, making it a critical target for studies in endocrinology, reproductive biology, and cancer research. The use of this antibody in Western blot and immunohistochemistry applications allows for precise and accurate detection of PRLR expression levels, providing valuable insights into its function and potential therapeutic implications.
By understanding the role of PRLR in different physiological and pathological conditions, researchers can effectively develop targeted therapies for endocrine disorders, reproductive health issues, and hormone-sensitive cancers. The Anti-PRLR Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0288) offers a powerful tool for investigating the complex mechanisms underlying PRLR signaling and its implications in various health-related conditions.
SKU:
HDAB0288
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC462
Synonyms:
Prolactin receptor, PRL-R
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
