The PRK2/PKN2 Polyclonal Antibody (CAB19746) is a valuable tool for researchers studying the PRK2/PKN2 protein, a key regulator of cell signaling pathways involved in various cellular processes. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the PRK2/PKN2 protein, researchers can detect and analyze its expression in different cell types, making it suitable for use in studies related to cell signaling, cancer research, and drug development.
PRK2/PKN2 is a serine/threonine protein kinase that plays a crucial role in regulating cell growth, differentiation, and migration. Its involvement in signaling pathways implicated in cancer progression and metastasis highlights its potential as a therapeutic target for cancer treatment. By understanding the function of PRK2/PKN2, researchers can potentially develop targeted therapies that disrupt its activity and inhibit tumor growth in various types of cancer.
Product Name:
PRK2/PKN2 Rabbit Monoclonal Antibody
SKU:
CAB19746
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PRK2/PKN2 (Q16513).
Apical junction complex, Centrosome, Cytoplasm, Cytosol, Intermediate filament cytoskeleton, Nuclear body, Nucleoplasm, Nucleus, Perinuclear region of cytoplasm, Plasma membrane
Calculated MW:
112kDa
Observed MW:
112kDa
Enables RNA polymerase binding activity; histone deacetylase binding activity; and protein serine/threonine kinase activity. Involved in several processes, including apical junction assembly; positive regulation of cell cycle; and positive regulation of viral genome replication. Located in several cellular components, including cleavage furrow; cytoskeleton; and midbody.
Purification Method:
Affinity purification
Gene ID:
5586
Clone Number:
ARC2274
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PRK2/PRK2/PKN2 Rabbit mAb (CAB19746) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
