The PQBP1 Polyclonal Antibody (CAB20776) is a valuable tool for researchers studying the PQBP1 protein, which is known for its role in intellectual disability and cognitive disorders. This antibody, produced in rabbits, is highly specific to human samples and is suitable for Western blot applications. By targeting the PQBP1 protein, this antibody enables the detection and analysis of this important molecule in various cell types.PQBP1 is a crucial factor in brain development and function, and its dysregulation is linked to conditions such as Renpenning syndrome and Golabi-Ito-Hall syndrome.
Research on PQBP1 is essential for understanding the molecular mechanisms underlying these disorders and potentially developing targeted therapies. By using the PQBP1 Polyclonal Antibody, researchers can further explore the functions and interactions of PQBP1, advancing our knowledge of these complex neurological conditions.
Product Name:
PQBP1 Monoclonal Antibody
SKU:
CAB20776
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human PQBP1 (NP_001027553.1).
This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked cognitive disability. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
10084
Clone Number:
ARC2697
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PQBP1 Rabbit mAb (CAB20776) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
