The Anti-PPP1R3C Antibody (CAB20458) is a high-quality polyclonal antibody designed for research involving PPP1R3C, a protein involved in regulating glycogen metabolism and energy balance. This antibody, raised in rabbits, is specific for human samples and has been validated for use in Western blot applications. It binds specifically to the PPP1R3C protein, allowing for accurate detection and analysis in various cell types.PPP1R3C, also known as protein phosphatase 1 regulatory subunit 3C, plays a crucial role in regulating glycogen synthesis and breakdown in cells. Dysregulation of PPP1R3C has been linked to metabolic disorders such as diabetes and obesity, making it a potential target for research in these areas.
By studying the function and activity of PPP1R3C, researchers can gain valuable insights into metabolic processes and potentially identify new therapeutic targets for these conditions.Overall, the Anti-PPP1R3C Antibody (CAB20458) is a valuable tool for researchers in the fields of metabolism, diabetes, and obesity, allowing for accurate and reliable detection of PPP1R3C in experimental settings. Its high specificity and sensitivity make it ideal for studies aiming to better understand the role of PPP1R3C in metabolic disorders and related conditions.
Product Name:
PPP1R3C Rabbit Polyclonal Antibody
SKU:
CAB20458
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PPP1R3C (NP_005389.1).
This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease.
Purification Method:
Affinity purification
Gene ID:
5507
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Rat kidney using PPP1R3C Rabbit pAb (CAB20458) at dilution of 1:50 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
