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PPM1G Monoclonal Antibody (CAB20959)

SKU:
CAB20959
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
$215 - $563
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:PPM1G Monoclonal Antibody
SKU:CAB20959
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 301-450 of human PPM1G (O15355).
Sequence:AEED DEEE EEEM MVPG MEGK EEPG SDSG TTAV VALI RGKQ LIVA NAGD SRCV VSEA GKAL DMSY DHKP EDEV ELAR IKNA GGKV TMDG RVNG GLNL SRAI GDHF YKRN KNLP PEEQ MISA LPDI KVLT LTDD HEFM VIAC DGIW NVMS SQ
Tested Applications:WB ELISA
Recommended Dilution:WB,1:100 - 1:500
Synonyms:PP2CG; PPP2CG; PP2CGAMMA; PPM1G
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Lipid-anchor, Membrane.
Calculated MW:59kDa
Observed MW:75kDa

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.

Purification Method:Affinity purification
Gene ID:5496
Clone Number:ARC2947
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various lysates, using PPM1G antibody (CAB20959) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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