The Anti-PP2A Alpha/Beta Antibody (CAB6175) is a powerful tool for researchers studying protein phosphatase 2A (PP2A), an enzyme complex with diverse roles in cellular processes such as cell growth, cell cycle regulation, and apoptosis. This polyclonal antibody, generated in rabbits, is highly specific for the alpha and beta isoforms of PP2A in human samples, making it ideal for Western blot applications.PP2A is known to play a crucial role in various signaling pathways, making it a key target for studies in areas such as cancer biology, neurobiology, and metabolism. By detecting and quantifying the alpha and beta isoforms of PP2A, researchers can gain valuable insights into the function and regulation of this important enzyme complex.
With its high reactivity and specificity, the Anti-PP2A Alpha/Beta Antibody (CAB6175) is a valuable tool for investigating the roles of PP2A in normal cellular function and disease processes. Its use in Western blot applications allows for accurate detection and quantification of PP2A alpha/beta isoforms, enabling researchers to further explore the complex functions of this enzyme in various biological contexts.
Product Name:
PP2A alpha + beta Rabbit Monoclonal Antibody
SKU:
CAB6175
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-309 of human PP2A alpha + beta (P62714).
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010]
Purification Method:
Affinity purification
Gene ID:
5516/5515
Clone Number:
ARC1889
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PP2A alpha + beta Rabbit mAb (CAB6175) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
