PON1 Rabbit Monoclonal Antibody (CAB3441)
- SKU:
- CAB3441
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ESA
- MVCD5
- PON
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PON1 Rabbit Monoclonal Antibody |
SKU: | CAB3441 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PON1 (P27169). |
Sequence: | TGSE DLEI LPNG LAFI SSGL KYPG IKSF NPNS PGKI LLMD LNEE DPTV LELG ITGS KFDV SSFN PHGI STFT DEDN AMYL LVVN HPDA KSTV ELFK FQEE E |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ESA; PON; MVCD5; PON1 |
Positive Sample: | Mouse liver,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular space. |
Calculated MW: | 40kDa |
Observed MW: | 40kDa |
This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7.
Purification Method: | Affinity purification |
Gene ID: | 5444 |
Clone Number: | ARC2001 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |