PODXL Rabbit Monoclonal Antibody (CAB4554)
- SKU:
- CAB4554
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- Gp200
- PC
- PCLP
- PCLP-1
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PODXL Rabbit Monoclonal Antibody |
SKU: | CAB4554 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-479 of human PODXL (O00592). |
Sequence: | SPAT ALRT PTLP ETMS SSPT AAST THRY PKTP SPTV AHES NWAK CEDL ETQT QSEK QLVL NLTG NTLC AGGA SDEK LISL ICRA VKAT FNPA QDKC GIRL ASVP GSQT VVVK EITI HTKL PAKD VYER LKDK WDEL KEAG VSDM KLGD QGPP EEAE DRFS MPLI ITIV CMAS FLLL VAAL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | PC; PDX; PCLP; Gp200; gp135; PCLP-1; PODXL1; PODXL |
Positive Sample: | HCT 116,293T,U-251MG |
Conjugate: | Unconjugated |
Cellular Localization: | apical plasma membrane, cytoplasm, extracellular exosome, extracellular space, microvillus membrane, nucleolus, plasma membrane, slit diaphragm |
Calculated MW: | 59kDa |
Observed MW: | 200-400kDa |
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
Purification Method: | Affinity purification |
Gene ID: | 5420 |
Clone Number: | ARC1031 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |