The Pleckstrin Polyclonal Antibody (CAB20905) is a valuable tool for researchers studying Pleckstrin, a protein involved in intracellular signaling pathways. This antibody, produced in rabbits, shows high reactivity with human samples and is suitable for Western blot applications. By binding to Pleckstrin, this antibody allows for the detection and analysis of this important protein in a variety of cell types.Pleckstrin plays a key role in regulating cell signaling processes, including cell growth, differentiation, and migration. Dysregulation of Pleckstrin has been implicated in various diseases, including cancer, cardiovascular disorders, and neurological conditions.
By studying the functions of Pleckstrin, researchers can gain insights into the mechanisms underlying these diseases and potentially identify novel therapeutic targets.Overall, the Pleckstrin Polyclonal Antibody is a valuable tool for researchers interested in exploring the roles of Pleckstrin in cellular signaling and disease pathogenesis. Its high reactivity and specificity make it a reliable reagent for studies in cell biology, molecular biology, and drug discovery.
Product Name:
Pleckstrin Monoclonal Antibody
SKU:
CAB20905
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Pleckstrin (P08567).
Enables phosphatidylinositol-3,4-bisphosphate binding activity; protein homodimerization activity; and protein kinase C binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; actin cytoskeleton organization; and positive regulation of supramolecular fiber organization. Located in cytoplasm and ruffle membrane.
Purification Method:
Affinity purification
Gene ID:
5341
Clone Number:
ARC2870
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Pleckstrin antibody (CAB20905) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
