PKM2-specific Rabbit Polyclonal Antibody (CAB18799)
- SKU:
- CAB18799
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PK3
- TCB
- p58
- OIP3
- PKM2
- CTHBP
- THBP1
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PKM2-specific Rabbit Polyclonal Antibody |
SKU: | CAB18799 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 380-480 of human PKM2-specific (NP_002645.3). |
Sequence: | LIAR EAEA AIYH LQLF EELR RLAP ITSD PTEA TAVG AVEA SFKC CSGA IIVL TKSG RSAH QVAR YRPR APII AVTR NPQT ARQA HLYR GIFP VLCK DPVQ E |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1; HEL-S-30; PKM2-specific |
Positive Sample: | HeLa,293T,A-549,NIH/3T3,C6,Mouse skeletal muscle,Mouse heart,Rat skeletal muscle,Rat heart |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 58kDa |
Observed MW: | 58kDa |
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
Purification Method: | Affinity purification |
Gene ID: | 5315 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |