PKM1-specific Rabbit Polyclonal Antibody (CAB18800)
- SKU:
- CAB18800
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PK3
- TCB
- p58
- OIP3
- PKM2
- CTHBP
- THBP1
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PKM1-specific Rabbit Polyclonal Antibody |
SKU: | CAB18800 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PKM1-specific (NP_001193728.1). |
Sequence: | GSDV ANAV LDGA DCIM LSGE TAKG DYPL EAVR MQHL IARE AEAA MFHR KLFE ELVR ASSH STDL MEAM AMGS VEAS YKCL AAAL IVLT ESGR SAHQ VARY R |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1; HEL-S-30; PKM1-specific |
Positive Sample: | Mouse skeletal muscle,Mouse heart,Rat skeletal muscle |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 58kDa |
Observed MW: | 58kDa |
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
Purification Method: | Affinity purification |
Gene ID: | 5315 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |