The PIK3R4/VPS15 Polyclonal Antibody (CAB5922) is a valuable tool for researchers studying the PIK3R4/VPS15 protein, which plays a crucial role in regulating various cellular processes, including vesicle trafficking and autophagy. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.The PIK3R4/VPS15 protein is a key component of the class III phosphatidylinositol 3-kinase (PI3K) complex, which is involved in the regulation of autophagy, a process that helps cells maintain homeostasis by degrading and recycling damaged organelles and proteins.
Dysregulation of autophagy has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic conditions.By using the PIK3R4/VPS15 Polyclonal Antibody, researchers can detect and analyze the expression of this protein in different cell types, providing valuable insights into its function and potential implications in disease pathogenesis. This antibody is an essential tool for studies in cell biology, molecular biology, and drug development aimed at targeting the PI3K complex for therapeutic purposes.
Product Name:
PIK3R4/VPS15 Rabbit Monoclonal Antibody
SKU:
CAB5922
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1259-1358 of human PIK3R4/VPS15 (Q99570).
Autophagosome, axoneme, cytosol, late endosome, microtubule cytoskeleton
Calculated MW:
153kDa
Observed MW:
153kDa
Predicted to enable protein serine/threonine kinase activity. Involved in positive regulation of phosphatidylinositol 3-kinase activity; receptor catabolic process; and regulation of cytokinesis. Located in late endosome and microtubule cytoskeleton.
Purification Method:
Affinity purification
Gene ID:
30849
Clone Number:
ARC2090
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PIK3R4/VPS15 Rabbit mAb (CAB5922) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
