PIAS1+PIAS2 Rabbit Monoclonal Antibody (CAB9670)
- SKU:
- CAB9670
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DDXBP1
- GBP
- GU/RH-II
- ZMIZ3
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PIAS1+PIAS2 Rabbit Monoclonal Antibody |
SKU: | CAB9670 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 552-651 of human PIAS1+PIAS2 (O75925). |
Sequence: | DNQH YNTS LLAA AAAA VSDD QDLL HSSR FFPY TSSQ MFLD QLSA GGST SLPT TNGS SSGS NSSL VSSN SLRE SHSH TVTN RSST DTAS IFGI IPDI ISLD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | DDXBP1; GBP; GU/RH-II; ZMIZ3; PIAS1+PIAS2 |
Positive Sample: | HepG2,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | nuclear speck, nucleoplasm, nucleus, PML body |
Calculated MW: | 76kDa |
Observed MW: | 76kDa |
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Purification Method: | Affinity purification |
Gene ID: | 8554/ 9063 |
Clone Number: | ARC1690 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |