The Anti-PIAS1/PIAS2 Antibody (CAB9670) is a valuable tool for researchers studying the protein inhibitors of activated STAT (PIAS) family members PIAS1 and PIAS2. These proteins play key roles in the regulation of transcription factors involved in immune responses, inflammation, and cellular proliferation. By targeting PIAS1 and PIAS2, this antibody allows for the detection and analysis of these important regulatory proteins in a variety of cell types.Raised in rabbits, this polyclonal antibody is highly specific and reactive with human samples, making it a reliable option for experiments such as Western blotting. Its ability to bind to PIAS1 and PIAS2 proteins enables researchers to investigate their functions and interactions, providing insights into the mechanisms underlying immune regulation and disease pathology.
The Anti-PIAS1/PIAS2 Antibody is an essential tool for studies in immunology, cancer research, and other fields where understanding the molecular pathways that govern immune responses is crucial. By targeting PIAS1 and PIAS2, researchers can uncover new therapeutic targets and develop interventions for conditions such as cancer, autoimmune disorders, and inflammatory diseases. Unlock the potential of PIAS proteins with this reliable and validated antibody for your research needs.
Product Name:
PIAS1+PIAS2 Rabbit Monoclonal Antibody
SKU:
CAB9670
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 552-651 of human PIAS1+PIAS2 (O75925).
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Purification Method:
Affinity purification
Gene ID:
8554/ 9063
Clone Number:
ARC1690
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PIAS1+PIAS2 Rabbit mAb (CAB9670) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
