The Anti-PI3 Kinase p110 Delta Antibody (CAB19742) is a valuable tool for researchers studying the PI3 Kinase pathway, specifically targeting the p110 Delta isoform. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the p110 Delta protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in cancer research and immunology.The PI3 Kinase pathway, particularly the p110 Delta isoform, plays a critical role in cell growth, proliferation, and survival.
Dysregulation of this pathway has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions. Understanding the activity of p110 Delta is essential for developing targeted therapies that can effectively inhibit or modulate its function in disease contexts.Overall, the Anti-PI3 Kinase p110 Delta Antibody (CAB19742) provides researchers with a reliable tool to investigate the role of the PI3 Kinase pathway in health and disease, with potential implications for the development of novel therapeutic strategies.
Product Name:
PI3 Kinase p110 delta Rabbit Monoclonal Antibody
SKU:
CAB19742
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human PI3 Kinase p110 delta (O00329).
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.
Purification Method:
Affinity purification
Gene ID:
5293
Clone Number:
ARC2268
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse thymus, using PI3 Kinase p110 delta Rabbit mAb (CAB19742) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
