The Anti-Phospholipid Scramblase 1 (PLSCR1) Antibody (CAB3430) is a crucial tool for researchers studying the role of PLSCR1 in cell biology and signaling pathways. This polyclonal antibody, produced in rabbits, demonstrates high specificity and sensitivity in detecting PLSCR1 protein in various experimental settings, including Western blot analysis.PLSCR1 is a phospholipid scramblase enzyme that plays essential roles in lipid metabolism, cell signaling, and membrane dynamics. It is involved in various cellular processes, including cell proliferation, apoptosis, and inflammatory responses.
Dysregulation of PLSCR1 expression has been linked to diseases such as cancer, cardiovascular disorders, and immune-related conditions.By using the Anti-Phospholipid Scramblase 1 Antibody, researchers can gain valuable insights into the function and regulation of PLSCR1 in physiological and pathological conditions. This antibody is an invaluable tool for investigations into cell membrane biology, lipid signaling, and disease mechanisms, paving the way for the development of novel therapeutic strategies targeting PLSCR1-mediated pathways.
Cell membrane, Nucleus, Cytoplasm, Cytoplasm, perinuclear region
Calculated MW:
35kDa
Observed MW:
35kDa
This gene encodes a phospholipid scramblase family member. The encoded protein is involved in disruption of the asymmetrical distribution of phospholipids between the inner and outer leaflets of the plasma membrane, resulting in externalization of phosphatidylserine. This cell membrane disruption plays an important role in the blood coagulation cascade as well as macrophage clearing of apoptotic cells. The encoded protein has additionally been implicated in gene regulation and interferon-induced antiviral responses.
Purification Method:
Affinity purification
Gene ID:
5359
Clone Number:
ARC2028
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from HT-29 cells, using Phospholipid Phospholipid Scramblase 1 (PLSCR1) (PLSCR1) Rabbit mAb (CAB3430) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
