Phospho-RIPK1/RIP-S166 Rabbit Polyclonal Antibody (CABP1230)
- SKU:
- CABP1230
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- RIP
- RIP-1
- RIP1
- RIPK1
Frequently bought together:
Description
Product Name: | Phospho-RIPK1/RIP-S166 Rabbit Polyclonal Antibody |
SKU: | CABP1230 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic phosphorylated peptide around S166 of human RIPK1/RIP (NP_003795.2). |
Sequence: | MWSK L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | RIP; RIP1; AIEFL; IMD57; RIP-1; Phospho-RIPK1/RIP-S166 |
Positive Sample: | HT-29+Z-VAD+TNF-α+SM-164 |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, mitochondrion, plasma membrane, ripoptosome |
Calculated MW: | 76kDa |
Observed MW: | 75kDa |
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth.
Purification Method: | Affinity purification |
Gene ID: | 8737 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |