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Phospho-PAK1/2/3-S144/S141/S139 Rabbit Monoclonal Antibody (CABP1158)

SKU:
CABP1158
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
PAKalpha
Research Area:
Cell Death
$503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospho-PAK1/2/3-S144/S141/S139 Rabbit Monoclonal Antibody
SKU:CABP1158
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic phosphorylated peptide around S144 of human PAK1PAK1 (Q13153).
Sequence:YMSF T
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:PAKalpha; Phospho-PAK1/2/3-S144/S141/S139
Positive Sample:NIH/3T3
Conjugate:Unconjugated
Cellular Localization:cytoplasm, cytosol, focal adhesion, microtubule organizing center, nuclear membrane, nucleoplasm, plasma membrane, ruffle membrane, Z disc
Calculated MW:65kDa
Observed MW:65kDa

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

Purification Method:Affinity purification
Gene ID:5058/5062/5063
Clone Number:ARC1698
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Phospho-PAK1/2/3-S144/S141/S139 Rabbit mAb (CABP1158) at 1:1000 dilution.NIH/3T3 cells were treated by Forskolin (30 uM) at 37℃ for 30 minutes after serum-starvation overnightSecondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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