Phospho-IRS1-S636/639 Rabbit Polyclonal Antibody (CABP0551)
- SKU:
- CABP0551
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- HIRS-1
- IRS1
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Product Name: | Phospho-IRS1-S636/639 Rabbit Polyclonal Antibody |
| SKU: | CABP0551 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human |
| Immunogen: | A synthetic phosphorylated peptide around S636 & S639 of human IRS1 (NP_005535.1). |
| Sequence: | MSPK SV |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:100 - 1:500 |
| Synonyms: | HIRS-1; Phospho-IRS1-S636/639 |
| Positive Sample: | 293T |
| Conjugate: | Unconjugated |
| Cellular Localization: | caveola, cytoplasm, cytosol, nucleoplasm, nucleus, plasma membrane |
| Calculated MW: | 132kDa |
| Observed MW: | 180kDa |
This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.
| Purification Method: | Affinity purification |
| Gene ID: | 3667 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
 | Western blot analysis of lysates from 293T cells, using Phospho-IRS1-S636/639 Rabbit pAb (CABP0551) at 1:500 dilution.293T cells were treated by IGF-1 (50 ng/ml) at 37℃ for 5 minutes after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s. |
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