null

Phospho-IP3R-S1756 Polyclonal Antibody (CABP1224)

SKU:
CABP1224
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ITPR1
ACV
CLA4
INSP3R1
IP3R
IP3R1
PPP1R94
SCA15
SCA16
SCA29
Research Area:
Cell Death
$155 - $587
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospho-IP3R-S1756 Polyclonal Antibody
SKU:CABP1224
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:A synthetic phosphorylated peptide around S1756 of human ITPR1 (XP_011531986.1).
Sequence:RESL T
Tested Applications:WB ELISA
Recommended Dilution:WB,1:100 - 1:500
Synonyms:ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94; Phospho-IP3R-S1756
Positive Sample:HeLa
Conjugate:Unconjugated
Cellular Localization:endoplasmic reticulum, nucleolus, perinuclear region of cytoplasm, Schaffer collateral - CA1 synapse
Calculated MW:314kDa
Observed MW:320kDa

This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

Purification Method:Affinity purification
Gene ID:3708
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using Phospho-IP3R-S1756 antibody (CABP1224) at 1:400 dilution.HeLa cells were treated by Forskolin (10 uM) at 37℃ for 1 hour after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

Related Products