Phospho-IκBα-S36 Rabbit Monoclonal Antibody (CABP0999)
- SKU:
- CABP0999
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | Phospho-IκBα-S36 Rabbit Monoclonal Antibody |
SKU: | CABP0999 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around S36 of human IκBα (P25963). |
Sequence: | LDSM K |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | IKBA; MAD-3; NFKBI; EDAID2; Phospho-IκBα-S36 |
Positive Sample: | THP-1+LPS,THP-1+PMA,NIH/3T3+TNF-α,C6+TNF-α |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 36kDa |
Observed MW: | 39kDa |
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Purification Method: | Affinity purification |
Gene ID: | 4792 |
Clone Number: | ARC1543 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |