The Anti-Phospho HSL (S660) Antibody (CABP1242) is a valuable tool for researchers studying hormone-sensitive lipase (HSL) phosphorylation at serine 660 (S660). HSL is a key enzyme involved in the regulation of lipid metabolism and energy balance. Phosphorylation at S660 is known to regulate HSL activity, making it critical for understanding lipid metabolism and related diseases like obesity and diabetes.This polyclonal antibody, raised in rabbits, is highly specific for detecting phosphorylated HSL at S660 in human samples. Validated for use in Western blot applications, it allows for precise detection and quantification of phospho-HSL levels in various cell types.
Researchers working in the fields of metabolism, obesity, diabetes, and lipid biology will find this antibody indispensable for their studies.The Anti-Phospho HSL (S660) Antibody opens up new avenues for exploring the role of HSL phosphorylation in metabolic disorders and identifying potential therapeutic targets for treating these conditions. Its high specificity and sensitivity make it a valuable asset for advancing research in the field of lipid metabolism and metabolic diseases.
Product Name:
Phospho-HSL-S660 Rabbit Polyclonal Antibody
SKU:
CABP1242
Size:
100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthesized peptide derived from human HSL (Phospho-Ser660)
The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids.
Purification Method:
Affinity purification
Gene ID:
3991
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.4.
Western blot analysis of lysates from HeLa cells, using Phospho-HSL-S660 Rabbit pAb (CABP1242) at 1:1000 dilution.HeLa cells were treated by TNF-α (20 ng/ml) at 37℃ for 30 minutes.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
