Phospho-Cdc6-S54 Rabbit Monoclonal Antibody (CABP1153)
- SKU:
- CABP1153
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CDC18L
- HsCDC18
- HsCDC6
- MGORS5
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | Phospho-Cdc6-S54 Rabbit Monoclonal Antibody |
SKU: | CABP1153 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic phosphorylated peptide around S54 of human Cdc6 (Q99741). |
Sequence: | PLSP R |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CDC18L; HsCDC6; MGORS5; HsCDC18; Phospho-Cdc6-S54 |
Positive Sample: | NIH/3T3 Paclitaxel,NIH/3T3 Hydroxyurea |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus |
Calculated MW: | 63kDa |
Observed MW: | 63kDa |
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
Purification Method: | Affinity purification |
Gene ID: | 990 |
Clone Number: | ARC1693 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |